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Oxidative Stress-Induced HMGB1 Translocation in Myenteric Neurons Contributes to Neuropathy in Colitis
High-mobility group box 1 (HMGB1) is a damage-associated molecular pattern released by dying cells to stimulate the immune response. During cell death, HMGB1 is translocated from the nucleus to the cytoplasm and passively released. High levels of secreted HMGB1 are observed in the faeces of inflamma...
Autores principales: | Stavely, Rhian, Sahakian, Lauren, Filippone, Rhiannon T., Stojanovska, Vanesa, Bornstein, Joel C., Sakkal, Samy, Nurgali, Kulmira |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776169/ https://www.ncbi.nlm.nih.gov/pubmed/36551259 http://dx.doi.org/10.3390/biom12121831 |
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