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Depression-Associated Negr1 Gene-Deficiency Induces Alterations in the Monoaminergic Neurotransmission Enhancing Time-Dependent Sensitization to Amphetamine in Male Mice

In GWAS studies, the neural adhesion molecule encoding the neuronal growth regulator 1 (NEGR1) gene has been consistently linked with both depression and obesity. Although the linkage between NEGR1 and depression is the strongest, evidence also suggests the involvement of NEGR1 in a wide spectrum of...

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Detalles Bibliográficos
Autores principales: Kaare, Maria, Jayaram, Mohan, Jagomäe, Toomas, Singh, Katyayani, Kilk, Kalle, Mikheim, Kaie, Leevik, Marko, Leidmaa, Este, Varul, Jane, Nõmm, Helis, Rähn, Kristi, Visnapuu, Tanel, Plaas, Mario, Lilleväli, Kersti, Schäfer, Michael K. E., Philips, Mari-Anne, Vasar, Eero
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776224/
https://www.ncbi.nlm.nih.gov/pubmed/36552158
http://dx.doi.org/10.3390/brainsci12121696