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Reliable and Fast Genotyping Protocol for Galactosylceramidase (Galc) in the Twitcher (Twi) Mouse

Twitcher (Twi) is a neurological Krabbe disease (KD, or globoid cell leukodystrophy) spontaneous mutant line in mice. The genome of the Twi mouse presents a single nucleotide polymorphism (SNP), leading to an enzymatically inactive galactosylceramidase (Galc) protein that causes KD. In this context,...

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Detalles Bibliográficos
Autores principales:	Carpi, Sara, Del Grosso, Ambra, De Sarlo, Miriam, Colagiorgio, Laura, Scaccini, Luca, Tonazzini, Ilaria, Parlanti, Gabriele, Cecchini, Marco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776230/ https://www.ncbi.nlm.nih.gov/pubmed/36551902 http://dx.doi.org/10.3390/biomedicines10123146

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