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Methylene Blue Delivery Mediated by Focused Ultrasound-Induced Blood–Brain Barrier Disruption Reduces Neural Damage and Amyloid-Beta Plaques by AQP-4 Upregulation

Alzheimer’s disease (AD) is the most prevalent neurodegenerative disease worldwide, causing progressive cognitive decline, memory impairment, and neurological deficits. Methylene blue (MB), an antioxidant, has emerged as a potential drug for the treatment of AD owing to its cognitive improvement and...

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Detalles Bibliográficos
Autores principales: Choi, Hyo Jin, Han, Mun, Jung, Byeongjin, Hong, Yu-Ri, Shin, Seulgi, Lim, Sungsu, Lee, Eun-Hee, Kim, Yun Kyung, Park, Juyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776289/
https://www.ncbi.nlm.nih.gov/pubmed/36551947
http://dx.doi.org/10.3390/biomedicines10123191