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Anti-Programmed Cell Death-1 Antibody and Dasatinib Combination Therapy Exhibits Efficacy in Metastatic Colorectal Cancer Mouse Models

SIMPLE SUMMARY: Cancer-associated fibroblasts (CAFs) are abundant in colorectal cancer (CRC) tissues and are essential for tumor growth. Histological analysis of CRC clinical specimens showed that the number of CAFs in liver metastases correlated with the number of CAFs in primary tumors. We hypothe...

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Detalles Bibliográficos
Autores principales: Kadota, Hiroki, Yuge, Ryo, Shimizu, Daisuke, Miyamoto, Ryo, Otani, Rina, Hiyama, Yuichi, Takigawa, Hidehiko, Hayashi, Ryohei, Urabe, Yuji, Kitadai, Yasuhiko, Oka, Shiro, Tanaka, Shinji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776338/
https://www.ncbi.nlm.nih.gov/pubmed/36551634
http://dx.doi.org/10.3390/cancers14246146