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PICALM rs3851179 Variants Modulate Left Postcentral Cortex Thickness, CSF Amyloid β42, and Phosphorylated Tau in the Elderly

PICALM rs3851179, one of the genes most frequently linked to susceptibility of late-onset Alzheimer’s disease (LOAD), plays a crucial role in regulating amyloid precursor protein, and amyloid β (Aβ) transcytosis. To explore the effects of PICALM and AD continuum stage on cortex thickness, CSF Aβ, an...

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Detalles Bibliográficos
Autores principales: Wu, Zhiwei, Yang, Yiwen, Song, Ziyang, Ma, Mengya, Feng, Mengmeng, Liu, Yuanqing, Xing, Hanqi, Chang, Yue, Dai, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776362/
https://www.ncbi.nlm.nih.gov/pubmed/36552141
http://dx.doi.org/10.3390/brainsci12121681