N6-Isopentenyladenosine Impairs Mitochondrial Metabolism through Inhibition of EGFR Translocation on Mitochondria in Glioblastoma Cells

SIMPLE SUMMARY: Glioblastomas are aggressive and incurable brain tumors, being resistant to therapy. N6-isopentenyladenosine (i6A or iPA) is a naturally derived molecule that has been studied for its anti-glioma effects. We found that iPA treatment induces an alteration of cellular metabolism due to...

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Detalles Bibliográficos
Autores principales: Pagano, Cristina, Coppola, Laura, Navarra, Giovanna, Avilia, Giorgio, Bruzzaniti, Sara, Piemonte, Erica, Galgani, Mario, Della Monica, Rosa, Chiariotti, Lorenzo, Cuomo, Mariella, Buonaiuto, Michela, Torelli, Giovanni, Caiazzo, Pasquale, Laezza, Chiara, Bifulco, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776489/
https://www.ncbi.nlm.nih.gov/pubmed/36551529
http://dx.doi.org/10.3390/cancers14246044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776489/
https://www.ncbi.nlm.nih.gov/pubmed/36551529
http://dx.doi.org/10.3390/cancers14246044

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