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Prostacyclin Released by Cancer-Associated Fibroblasts Promotes Immunosuppressive and Pro-Metastatic Macrophage Polarization in the Ovarian Cancer Microenvironment

SIMPLE SUMMARY: Reciprocal interactions between tumor and host cells in the tumor microenvironment critically influence the clinical outcome in ovarian carcinoma patients. Therefore, the identification of factors triggering central communication pathways controlling tumor growth and metastasis is hi...

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Detalles Bibliográficos
Autores principales: Sommerfeld, Leah, Knuth, Isabel, Finkernagel, Florian, Pesek, Jelena, Nockher, Wolfgang A., Jansen, Julia M., Wagner, Uwe, Nist, Andrea, Stiewe, Thorsten, Müller-Brüsselbach, Sabine, Müller, Rolf, Reinartz, Silke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776493/
https://www.ncbi.nlm.nih.gov/pubmed/36551640
http://dx.doi.org/10.3390/cancers14246154