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Methylation of TET2 Promoter Is Associated with Global Hypomethylation and Hypohydroxymethylation in Peripheral Blood Mononuclear Cells of Systemic Lupus Erythematosus Patients

(1) Background: It is widely accepted that aberrant methylation patterns contribute to the development of systemic lupus erythematosus (SLE). Ten–eleven translocation (TET) methylcytosine dioxygenase is an essential enzyme of which there are three members, TET1, 2, and 3, involved in hydroxymethylat...

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Detalles Bibliográficos
Autores principales: Sung, Wan-Yu, Lin, Yuan-Zhao, Hwang, Daw-Yang, Lin, Chia-Hui, Li, Ruei-Nian, Tseng, Chia-Chun, Wu, Cheng-Chin, Ou, Tsan-Teng, Yen, Jeng-Hsien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776498/
https://www.ncbi.nlm.nih.gov/pubmed/36553013
http://dx.doi.org/10.3390/diagnostics12123006