Tumoricidal, Temozolomide- and Radiation-Sensitizing Effects of K(Ca)3.1 K(+) Channel Targeting In Vitro Are Dependent on Glioma Cell Line and Stem Cell Fraction

SIMPLE SUMMARY: A potential new treatment for glioma patients is the blockade of K(Ca)3.1 potassium channels. In our study, we performed experiments with the K(Ca)3.1 blocker TRAM-34 in five glioma cell lines. To broaden our findings, effects on cultures enriched in glioma stem cells which are thoug...

Descripción completa

Detalles Bibliográficos
Autores principales: Stransky, Nicolai, Ganser, Katrin, Naumann, Ulrike, Huber, Stephan M., Ruth, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776522/
https://www.ncbi.nlm.nih.gov/pubmed/36551685
http://dx.doi.org/10.3390/cancers14246199

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776522/
https://www.ncbi.nlm.nih.gov/pubmed/36551685
http://dx.doi.org/10.3390/cancers14246199

Ejemplares similares