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Tumoricidal, Temozolomide- and Radiation-Sensitizing Effects of K(Ca)3.1 K(+) Channel Targeting In Vitro Are Dependent on Glioma Cell Line and Stem Cell Fraction

SIMPLE SUMMARY: A potential new treatment for glioma patients is the blockade of K(Ca)3.1 potassium channels. In our study, we performed experiments with the K(Ca)3.1 blocker TRAM-34 in five glioma cell lines. To broaden our findings, effects on cultures enriched in glioma stem cells which are thoug...

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Detalles Bibliográficos
Autores principales:	Stransky, Nicolai, Ganser, Katrin, Naumann, Ulrike, Huber, Stephan M., Ruth, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776522/ https://www.ncbi.nlm.nih.gov/pubmed/36551685 http://dx.doi.org/10.3390/cancers14246199

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