NEO212, a Perillyl Alcohol-Temozolomide Conjugate, Triggers Macrophage Differentiation of Acute Myeloid Leukemia Cells and Blocks Their Tumorigenicity

SIMPLE SUMMARY: Acute myeloid leukemia (AML) is a cancer of the blood and bone marrow, where cancer cells are unable to complete the maturation process towards white blood cells, but instead continue to proliferate. We are developing a novel chemotherapeutic drug, NEO212, that has shown anticancer a...

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Detalles Bibliográficos
Autores principales: Chen, Thomas C., Minea, Radu O., Swenson, Steve, Yang, Zhuoyue, Thein, Thu Zan, Schönthal, Axel H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776529/
https://www.ncbi.nlm.nih.gov/pubmed/36551551
http://dx.doi.org/10.3390/cancers14246065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776529/
https://www.ncbi.nlm.nih.gov/pubmed/36551551
http://dx.doi.org/10.3390/cancers14246065

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