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NEO212, a Perillyl Alcohol-Temozolomide Conjugate, Triggers Macrophage Differentiation of Acute Myeloid Leukemia Cells and Blocks Their Tumorigenicity
SIMPLE SUMMARY: Acute myeloid leukemia (AML) is a cancer of the blood and bone marrow, where cancer cells are unable to complete the maturation process towards white blood cells, but instead continue to proliferate. We are developing a novel chemotherapeutic drug, NEO212, that has shown anticancer a...
Autores principales: | Chen, Thomas C., Minea, Radu O., Swenson, Steve, Yang, Zhuoyue, Thein, Thu Zan, Schönthal, Axel H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776529/ https://www.ncbi.nlm.nih.gov/pubmed/36551551 http://dx.doi.org/10.3390/cancers14246065 |
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