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Real World Cost-Effectiveness Analysis of Population Screening for BRCA Variants among Ashkenazi Jews Compared with Family History-Based Strategies

SIMPLE SUMMARY: Identifying BRCA mutations carriers reduces cancer incidence by surveillance and prevention. We analyzed the cost-effectiveness of population screening (PS) for BRCA mutations in Ashkenazi Jews (AJ), for whom carrier rate is 2.5%, compared with existing strategies: cascade testing (C...

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Detalles Bibliográficos
Autores principales: Michaelson-Cohen, Rachel, Cohen, Matan J., Cohen, Carmit, Greenberg, Dan, Shmueli, Amir, Lieberman, Sari, Tomer, Ariela, Levy-Lahad, Ephrat, Lahad, Amnon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776581/
https://www.ncbi.nlm.nih.gov/pubmed/36551598
http://dx.doi.org/10.3390/cancers14246113