HDAC6 Inhibition Alleviates Ischemia- and Cisplatin-Induced Acute Kidney Injury by Promoting Autophagy

Histone deacetylase (HDAC) 6 exists exclusively in cytoplasm and deacetylates cytoplasmic proteins such as α-tubulin. HDAC6 dysfunction is associated with several pathological conditions in renal disorders, including UUO-induced fibrotic kidneys and rhabdomyolysis-induced nephropathy. However, the r...

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Detalles Bibliográficos
Autores principales: Shi, Lang, Song, Zhixia, Li, Chenglong, Deng, Fangjing, Xia, Yao, Huang, Jing, Wu, Xiongfei, Zhu, Jiefu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776591/
https://www.ncbi.nlm.nih.gov/pubmed/36552715
http://dx.doi.org/10.3390/cells11243951

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776591/
https://www.ncbi.nlm.nih.gov/pubmed/36552715
http://dx.doi.org/10.3390/cells11243951

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