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HDAC6 Inhibition Alleviates Ischemia- and Cisplatin-Induced Acute Kidney Injury by Promoting Autophagy
Histone deacetylase (HDAC) 6 exists exclusively in cytoplasm and deacetylates cytoplasmic proteins such as α-tubulin. HDAC6 dysfunction is associated with several pathological conditions in renal disorders, including UUO-induced fibrotic kidneys and rhabdomyolysis-induced nephropathy. However, the r...
Autores principales: | Shi, Lang, Song, Zhixia, Li, Chenglong, Deng, Fangjing, Xia, Yao, Huang, Jing, Wu, Xiongfei, Zhu, Jiefu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776591/ https://www.ncbi.nlm.nih.gov/pubmed/36552715 http://dx.doi.org/10.3390/cells11243951 |
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