Treatment with MDL 72527 Ameliorated Clinical Symptoms, Retinal Ganglion Cell Loss, Optic Nerve Inflammation, and Improved Visual Acuity in an Experimental Model of Multiple Sclerosis

Multiple Sclerosis (MS) is a highly disabling neurological disease characterized by inflammation, neuronal damage, and demyelination. Vision impairment is one of the major clinical features of MS. Previous studies from our lab have shown that MDL 72527, a pharmacological inhibitor of spermine oxidas...

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Detalles Bibliográficos
Autores principales: Liu, Fang, Alfarhan, Moaddey, Baker, Leanna, Shenoy, Nidhi, Liao, Yini, Henry-Ojo, Harry O., Somanath, Payaningal R., Narayanan, S. Priya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776605/
https://www.ncbi.nlm.nih.gov/pubmed/36552864
http://dx.doi.org/10.3390/cells11244100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776605/
https://www.ncbi.nlm.nih.gov/pubmed/36552864
http://dx.doi.org/10.3390/cells11244100

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