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Treatment with MDL 72527 Ameliorated Clinical Symptoms, Retinal Ganglion Cell Loss, Optic Nerve Inflammation, and Improved Visual Acuity in an Experimental Model of Multiple Sclerosis
Multiple Sclerosis (MS) is a highly disabling neurological disease characterized by inflammation, neuronal damage, and demyelination. Vision impairment is one of the major clinical features of MS. Previous studies from our lab have shown that MDL 72527, a pharmacological inhibitor of spermine oxidas...
Autores principales: | Liu, Fang, Alfarhan, Moaddey, Baker, Leanna, Shenoy, Nidhi, Liao, Yini, Henry-Ojo, Harry O., Somanath, Payaningal R., Narayanan, S. Priya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776605/ https://www.ncbi.nlm.nih.gov/pubmed/36552864 http://dx.doi.org/10.3390/cells11244100 |
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