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FLT3-ITD Measurable Residual Disease Monitoring in Acute Myeloid Leukemia Using Next-Generation Sequencing

SIMPLE SUMMARY: FLT3-ITD monitoring is essential in AML management, and there is a great need for sensitive monitoring methods. We present a simple and easily applicable ITD-tracing algorithm optimized for MRD monitoring based on the NGS method. Our assay is sensitive to 0.001% and has a superior pe...

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Detalles Bibliográficos
Autores principales: Lee, Jong-Mi, Park, Silvia, Hwang, Insik, Kang, Dain, Cho, Byung Sik, Kim, Hee-Je, Ahn, Ari, Kim, Myungshin, Kim, Yonggoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776673/
https://www.ncbi.nlm.nih.gov/pubmed/36551616
http://dx.doi.org/10.3390/cancers14246121