c-Abl Regulates the Pathological Deposition of TDP-43 via Tyrosine 43 Phosphorylation

Non-receptor tyrosine kinase, c-Abl plays a role in the pathogenesis of several neurodegenerative disorders such as Alzheimer’s disease and Parkinson’s disease. Here, we found that TDP-43, which was one of the main proteins comprising pathological deposits in amyotrophic lateral sclerosis (ALS), is...

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Detalles Bibliográficos
Autores principales: Lee, Saebom, Ryu, Hye Guk, Kweon, Sin Ho, Kim, Hyerynn, Park, Hyeonwoo, Lee, Kyung-Ha, Jang, Sang-Min, Na, Chan Hyun, Kim, Sangjune, Ko, Han Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776721/
https://www.ncbi.nlm.nih.gov/pubmed/36552734
http://dx.doi.org/10.3390/cells11243972

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776721/
https://www.ncbi.nlm.nih.gov/pubmed/36552734
http://dx.doi.org/10.3390/cells11243972

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