Hepatic Polarized Differentiation Promoted the Maturity and Liver Function of Human Embryonic Stem Cell-Derived Hepatocytes via Activating Hippo and AMPK Signaling Pathways

Hepatocytes exhibit a multi-polarized state under the in vivo physiological environment, however, human embryonic stem cell-derived hepatocytes (hEHs) rarely exhibit polarity features in a two-dimensional (2D) condition. Thus, we hypothesized whether the polarized differentiation might enhance the m...

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Detalles Bibliográficos
Autores principales: Wang, Jue, Situ, Ping, Chen, Sen, Wu, Haibin, Zhang, Xueyan, Liu, Shoupei, Wang, Yiyu, Xie, Jinghe, Chen, Honglin, Duan, Yuyou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776724/
https://www.ncbi.nlm.nih.gov/pubmed/36552880
http://dx.doi.org/10.3390/cells11244117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776724/
https://www.ncbi.nlm.nih.gov/pubmed/36552880
http://dx.doi.org/10.3390/cells11244117

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