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Real-Time Characterization of Clonal Fate Decisions in Complex Leukemia Samples by Fluorescent Genetic Barcoding

Clonal heterogeneity in acute myeloid leukemia (AML) forms the basis for treatment failure and relapse. Attempts to decipher clonal evolution and clonal competition primarily depend on deep sequencing approaches. However, this prevents the experimental confirmation of the identified disease-relevant...

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Detalles Bibliográficos
Autores principales: Maetzig, Tobias, Lieske, Anna, Dörpmund, Nicole, Rothe, Michael, Kleppa, Marc-Jens, Dziadek, Violetta, Hassan, Jacob Jalil, Dahlke, Julia, Borchert, Dorit, Schambach, Axel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776743/
https://www.ncbi.nlm.nih.gov/pubmed/36552809
http://dx.doi.org/10.3390/cells11244045