Drug Inhibition of Redox Factor-1 Restores Hypoxia-Driven Changes in Tuberous Sclerosis Complex 2 Deficient Cells

SIMPLE SUMMARY: Tuberous sclerosis complex (TSC) is a genetic disease where patients are predisposed to tumors and neurological complications. Current therapies for this disease are not fully curative. We aimed to explore novel drug targets and therapies that could further benefit TSC patients. This...

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Detalles Bibliográficos
Autores principales: Champion, Jesse D., Dodd, Kayleigh M., Lam, Hilaire C., Alzahrani, Mohammad A. M., Seifan, Sara, Rad, Ellie, Scourfield, David Oliver, Fishel, Melissa L., Calver, Brian L., Ager, Ann, Henske, Elizabeth P., Davies, David Mark, Kelley, Mark R., Tee, Andrew R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776744/
https://www.ncbi.nlm.nih.gov/pubmed/36551683
http://dx.doi.org/10.3390/cancers14246195

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776744/
https://www.ncbi.nlm.nih.gov/pubmed/36551683
http://dx.doi.org/10.3390/cancers14246195

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