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Drug Inhibition of Redox Factor-1 Restores Hypoxia-Driven Changes in Tuberous Sclerosis Complex 2 Deficient Cells
SIMPLE SUMMARY: Tuberous sclerosis complex (TSC) is a genetic disease where patients are predisposed to tumors and neurological complications. Current therapies for this disease are not fully curative. We aimed to explore novel drug targets and therapies that could further benefit TSC patients. This...
Autores principales: | Champion, Jesse D., Dodd, Kayleigh M., Lam, Hilaire C., Alzahrani, Mohammad A. M., Seifan, Sara, Rad, Ellie, Scourfield, David Oliver, Fishel, Melissa L., Calver, Brian L., Ager, Ann, Henske, Elizabeth P., Davies, David Mark, Kelley, Mark R., Tee, Andrew R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776744/ https://www.ncbi.nlm.nih.gov/pubmed/36551683 http://dx.doi.org/10.3390/cancers14246195 |
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