Paclitaxel Inhibits KCNQ Channels in Primary Sensory Neurons to Initiate the Development of Painful Peripheral Neuropathy

Cancer patients undergoing paclitaxel infusion usually experience peripheral nerve degeneration and serious neuropathic pain termed paclitaxel-induced peripheral neuropathy (PIPN). However, alterations in the dose or treatment schedule for paclitaxel do not eliminate PIPN, and no therapies are avail...

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Detalles Bibliográficos
Autores principales: Wu, Zizhen, Toro, Gabor, Xu, Guoying, Dang, Danny, Prater, Charmaine, Yang, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776748/
https://www.ncbi.nlm.nih.gov/pubmed/36552832
http://dx.doi.org/10.3390/cells11244067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776748/
https://www.ncbi.nlm.nih.gov/pubmed/36552832
http://dx.doi.org/10.3390/cells11244067

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