Cargando…

Paclitaxel Inhibits KCNQ Channels in Primary Sensory Neurons to Initiate the Development of Painful Peripheral Neuropathy

Cancer patients undergoing paclitaxel infusion usually experience peripheral nerve degeneration and serious neuropathic pain termed paclitaxel-induced peripheral neuropathy (PIPN). However, alterations in the dose or treatment schedule for paclitaxel do not eliminate PIPN, and no therapies are avail...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Zizhen, Toro, Gabor, Xu, Guoying, Dang, Danny, Prater, Charmaine, Yang, Qing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776748/ https://www.ncbi.nlm.nih.gov/pubmed/36552832 http://dx.doi.org/10.3390/cells11244067

Ejemplares similares

Nmnat mitigates sensory dysfunction in a Drosophila model of paclitaxel-induced peripheral neuropathy
por: Brazill, Jennifer M., et al.
Publicado: (2018)

Activation of peripheral KCNQ channels attenuates inflammatory pain
por: Hayashi, Hiroki, et al.
Publicado: (2014)

Activation of peripheral KCNQ channels relieves gout pain
por: Zheng, Yueming, et al.
Publicado: (2015)

Pathomechanisms of Paclitaxel-Induced Peripheral Neuropathy
por: Klein, Ines, et al.
Publicado: (2021)

Mechanisms Underlying Modulation of Neuronal KCNQ2/KCNQ3 Potassium Channels by Extracellular Protons
por: Prole, David L., et al.
Publicado: (2003)

KCNQ2 and KCNQ5 form heteromeric channels independent of KCNQ3
por: Soh, Heun, et al.
Publicado: (2022)

Longitudinal RNA Sequencing of Skin and DRG Neurons in Mice with Paclitaxel-Induced Peripheral Neuropathy
por: Cirrincione, Anthony M., et al.
Publicado: (2022)

Polarized Axonal Surface Expression of Neuronal KCNQ Potassium Channels Is Regulated by Calmodulin Interaction with KCNQ2 Subunit
por: Cavaretta, John P., et al.
Publicado: (2014)

Drosophila KCNQ Channel Displays Evolutionarily Conserved Electrophysiology and Pharmacology with Mammalian KCNQ Channels
por: Cavaliere, Sonia, et al.
Publicado: (2011)

Excitability of Aβ sensory neurons is altered in an animal model of peripheral neuropathy
por: Zhu, Yong Fang, et al.
Publicado: (2012)

The effectiveness of regional cooling for paclitaxel-induced peripheral neuropathy
por: Sato, Junya, et al.
Publicado: (2016)

2043: Pharmacokinetic prediction of paclitaxel-induced peripheral neuropathy
por: Hertz, Daniel L., et al.
Publicado: (2018)

PIP2 mediates functional coupling and pharmacology of neuronal KCNQ channels
por: Kim, Robin Y., et al.
Publicado: (2017)

Polygenic Inheritance of Paclitaxel-Induced Sensory Peripheral Neuropathy Driven by Axon Outgrowth Gene Sets in CALGB 40101 (Alliance)
por: Chhibber, Aparna, et al.
Publicado: (2014)

Charcot neuroarthropathy of the knee due to idiopathic sensory peripheral neuropathy
por: Yang, Qian-Hao, et al.
Publicado: (2019)

Management of Oxaliplatin-Induced Peripheral Sensory Neuropathy
por: Cavaletti, Guido, et al.
Publicado: (2020)

Peripheral Neuropathy Caused by Paclitaxel and Docetaxel: An Evaluation and Comparison of Symptoms
por: Tofthagen*, Cindy, et al.
Publicado: (2013)

Orofacial neuropathic pain induced by oxaliplatin: Downregulation of KCNQ2 channels in V2 trigeminal ganglion neurons and treatment by the KCNQ2 channel potentiator retigabine
por: Ling, Jennifer, et al.
Publicado: (2017)

Gating and Regulation of KCNQ1 and KCNQ1 + KCNE1 Channel Complexes
por: Wang, Yundi, et al.
Publicado: (2020)

Peripheral sensory neurons and non-neuronal cells express functional Piezo1 channels
por: Shin, Seung Min, et al.
Publicado: (2023)

Ion channels and neuronal hyperexcitability in chemotherapy-induced peripheral neuropathy: Cause and effect?
por: Aromolaran, Kelly A, et al.
Publicado: (2017)

Effect of certain trimethoxy flavones on paclitaxel - induced peripheral neuropathy in mice
por: Nadipelly, Jagan, et al.
Publicado: (2018)

Risk factors for paclitaxel-induced peripheral neuropathy in patients with breast cancer
por: Ghoreishi, Zohreh, et al.
Publicado: (2018)

Minoxidil is a potential neuroprotective drug for paclitaxel-induced peripheral neuropathy
por: Chen, Yi-Fan, et al.
Publicado: (2017)

Losartan attenuates neuroinflammation and neuropathic pain in paclitaxel‐induced peripheral neuropathy
por: Kalynovska, Nataliia, et al.
Publicado: (2020)

A Fenofibrate Diet Prevents Paclitaxel-Induced Peripheral Neuropathy in Mice
por: Caillaud, Martial, et al.
Publicado: (2020)

Preclinical and Clinical Evidence of Therapeutic Agents for Paclitaxel-Induced Peripheral Neuropathy
por: Kawashiri, Takehiro, et al.
Publicado: (2021)

Discovery of Potential Neuroprotective Agents against Paclitaxel-Induced Peripheral Neuropathy
por: Chen, Yi-Fan, et al.
Publicado: (2022)

Contribution of KCNQ and TREK Channels to the Resting Membrane Potential in Sympathetic Neurons at Physiological Temperature
por: Rivas-Ramírez, Paula, et al.
Publicado: (2020)

KCNQ2 channels regulate the population activity of neonatal GABAergic neurons ex vivo
por: Hou, Bowen, et al.
Publicado: (2023)

A Change in Configuration of the Calmodulin-KCNQ Channel Complex Underlies Ca(2+)-Dependent Modulation of KCNQ Channel Activity
por: Kosenko, Anastasia, et al.
Publicado: (2013)

Systematic review of the effectiveness of self-initiated interventions to decrease pain and sensory disturbances associated with peripheral neuropathy
por: Ogle, Theodora, et al.
Publicado: (2020)

Transcriptome analysis reveals dysregulation of inflammatory and neuronal function in dorsal root ganglion of paclitaxel-induced peripheral neuropathy rats
por: Sun, Wuping, et al.
Publicado: (2022)

A fruit fly model for studying paclitaxel-induced peripheral neuropathy and hyperalgesia
por: Hamoudi, Zina, et al.
Publicado: (2018)

Acupuncture for Paclitaxel-Induced Peripheral Neuropathy: A Review of Clinical and Basic Studies
por: Zhao, Yu-Xue, et al.
Publicado: (2021)

Loss of Auditory Activity Modifies the Location of Potassium Channel KCNQ5 in Auditory Brainstem Neurons
por: Caminos, Elena, et al.
Publicado: (2015)

Neuronal KCNQ2/3 channels are recruited to lipid raft microdomains by palmitoylation of BACE1
por: Dai, Gucan
Publicado: (2022)

Ca(V)3.2 T-Type Calcium Channels in Peripheral Sensory Neurons Are Important for Mibefradil-Induced Reversal of Hyperalgesia and Allodynia in Rats with Painful Diabetic Neuropathy
por: Obradovic, Aleksandar Lj., et al.
Publicado: (2014)

Statin use and peripheral sensory neuropathy: a pilot study
por: West, Brenton, et al.
Publicado: (2013)

Aberrant plasticity of peripheral sensory axons in a painful neuropathy
por: Hirai, Takashi, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_p4r89ise9b22dg7h1j743f66b1