Efficient and Safe Editing of Porcine Endogenous Retrovirus Genomes by Multiple-Site Base-Editing Editor

Gene-modified miniature pigs serve as alternative tissue and organ donors for xenotransplantation to alleviate the shortage of human allogenic organs. However, the high copy number of porcine endogenous retrovirus (PERV) genomes integrates with the porcine genome, which has a potential risk of cross...

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Detalles Bibliográficos
Autores principales: Zheng, Shuwen, Zhong, Haiwen, Zhou, Xiaoqing, Chen, Min, Li, Wansheng, Zi, Yin, Chi, Yue, Wang, Jinling, Zheng, Wei, Zou, Qingjian, Lai, Liangxue, Tang, Chengcheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776866/
https://www.ncbi.nlm.nih.gov/pubmed/36552739
http://dx.doi.org/10.3390/cells11243975

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776866/
https://www.ncbi.nlm.nih.gov/pubmed/36552739
http://dx.doi.org/10.3390/cells11243975

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