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eIF4A/PDCD4 Pathway, a Factor for Doxorubicin Chemoresistance in a Triple-Negative Breast Cancer Cell Model

Cells employ several adaptive mechanisms under conditions of accelerated cell division, such as the unfolded protein response (UPR). The UPR is composed of a tripartite signaling system that involves ATF6, PERK, and IRE1, which maintain protein homeostasis (proteostasis). However, deregulation of pr...

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Detalles Bibliográficos
Autores principales: González-Ortiz, Alina, Pulido-Capiz, Angel, Castañeda-Sánchez, César Y., Ibarra-López, Esmeralda, Galindo-Hernández, Octavio, Calderón-Fernández, Maritza Anahí, López-Cossio, Leslie Y., Díaz-Molina, Raul, Chimal-Vega, Brenda, Serafín-Higuera, Nicolás, Córdova-Guerrero, Iván, García-González, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776898/
https://www.ncbi.nlm.nih.gov/pubmed/36552834
http://dx.doi.org/10.3390/cells11244069