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Vascular Niche Facilitates Acquired Drug Resistance to c-Met Inhibitor in Originally Sensitive Osteosarcoma Cells

SIMPLE SUMMARY: Osteosarcoma (OS) is a common malignant bone tumor in adolescents whose survival rates have not improved over the past few decades. At present, there is a lack of effective molecule-targeted therapy. Abnormal activation of c-Met is often detected in patients with OS, and c-Met inhibi...

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Detalles Bibliográficos
Autores principales: Tang, Weifeng, Zhang, Yu, Zhang, Haixia, Zhang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776923/
https://www.ncbi.nlm.nih.gov/pubmed/36551686
http://dx.doi.org/10.3390/cancers14246201