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AP-2δ Is the Most Relevant Target of AP-2 Family-Focused Cancer Therapy and Affects Genome Organization

Formerly hailed as “undruggable” proteins, transcription factors (TFs) are now under investigation for targeted therapy. In cancer, this may alter, inter alia, immune evasion or replicative immortality, which are implicated in genome organization, a process that accompanies multi-step tumorigenesis...

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Detalles Bibliográficos
Autores principales: Kołat, Damian, Zhao, Lin-Yong, Kciuk, Mateusz, Płuciennik, Elżbieta, Kałuzińska-Kołat, Żaneta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9776946/
https://www.ncbi.nlm.nih.gov/pubmed/36552887
http://dx.doi.org/10.3390/cells11244124