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Antileukemic Activity of hsa-miR-203a-5p by Limiting Glutathione Metabolism in Imatinib-Resistant K562 Cells

Imatinib has been the first and most successful tyrosine kinase inhibitor (TKI) for chronic myeloid leukemia (CML), but many patients develop resistance to it after a satisfactory response. Glutathione (GSH) metabolism is thought to be one of the factors causing the emergence of imatinib resistance....

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Detalles Bibliográficos
Autores principales: Singh, Priyanka, Yadav, Radheshyam, Verma, Malkhey, Chhabra, Ravindresh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9777165/
https://www.ncbi.nlm.nih.gov/pubmed/36547099
http://dx.doi.org/10.3390/cimb44120438