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Effects of Simvastatin on Cartilage Homeostasis in Steroid-Induced Osteonecrosis of Femoral Head by Inhibiting Glucocorticoid Receptor

Steroid-induced osteonecrosis of femoral head (SONFH) is one of the most common bone disorders in humans. Statin treatment is beneficial in preventing the development of SONFH through anti-inflammation effects and inhibition of the glucocorticoid receptor (GR). However, potential mechanisms of stati...

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Detalles Bibliográficos
Autores principales: Yu, Yaling, Lin, Lishan, Liu, Kangping, Jiang, Yixin, Zhou, Zhenlei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9777187/
https://www.ncbi.nlm.nih.gov/pubmed/36552711
http://dx.doi.org/10.3390/cells11243945