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Male DAT Val559 Mice Exhibit Compulsive Behavior under Devalued Reward Conditions Accompanied by Cellular and Pharmacological Changes

Identified across multiple psychiatric disorders, the dopamine (DA) transporter (DAT) Ala559Val substitution triggers non-vesicular, anomalous DA efflux (ADE), perturbing DA neurotransmission and behavior. We have shown that DAT Val559 mice display a waiting impulsivity and changes in cognitive perf...

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Detalles Bibliográficos
Autores principales: Stewart, Adele, Davis, Gwynne L., Areal, Lorena B., Rabil, Maximilian J., Tran, Vuong, Mayer, Felix P., Blakely, Randy D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9777203/
https://www.ncbi.nlm.nih.gov/pubmed/36552823
http://dx.doi.org/10.3390/cells11244059