Cargando…
Male DAT Val559 Mice Exhibit Compulsive Behavior under Devalued Reward Conditions Accompanied by Cellular and Pharmacological Changes
Identified across multiple psychiatric disorders, the dopamine (DA) transporter (DAT) Ala559Val substitution triggers non-vesicular, anomalous DA efflux (ADE), perturbing DA neurotransmission and behavior. We have shown that DAT Val559 mice display a waiting impulsivity and changes in cognitive perf...
Autores principales: | Stewart, Adele, Davis, Gwynne L., Areal, Lorena B., Rabil, Maximilian J., Tran, Vuong, Mayer, Felix P., Blakely, Randy D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9777203/ https://www.ncbi.nlm.nih.gov/pubmed/36552823 http://dx.doi.org/10.3390/cells11244059 |
Ejemplares similares
-
Serotonin transporter inhibition and 5-HT(2C) receptor activation drive loss of cocaine-induced locomotor activation in DAT Val559 mice
por: Stewart, Adele, et al.
Publicado: (2018) -
Is dopamine transporter-mediated dopaminergic signaling in the retina a noninvasive biomarker for attention-deficit/ hyperactivity disorder? A study in a novel dopamine transporter variant Val559 transgenic mouse model
por: Dai, Heng, et al.
Publicado: (2017) -
Hypoalgesia Induced by Reward Devaluation in Rats
por: Jiménez-García, Ana María, et al.
Publicado: (2016) -
Selective Devaluation Affects the Processing of Preferred Rewards
por: Huvermann, Dana M., et al.
Publicado: (2021) -
Attentional capture by signals of reward persists following outcome devaluation
por: Watson, Poppy, et al.
Publicado: (2022)