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Elevated Monoamine Oxidase-A in Anterior Cingulate of Post-Mortem Human Parkinson’s Disease: A Potential Surrogate Biomarker for Lewy Bodies?

Lewy bodies (LB) play a neuropathological role in Parkinson’s disease (PD). Our goal was to evaluate LB using anti-ubiquitin immunohistochemistry (UIHC) and find correlations with monoamine oxidase-A (MAO-A) using imaging agent, [(18)F]FAZIN3. Human post-mortem anterior cingulate (AC) and corpus cal...

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Detalles Bibliográficos
Autores principales: Mukherjee, Jogeshwar, Ladwa, Reisha M., Liang, Christopher, Syed, Amina U.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9777299/
https://www.ncbi.nlm.nih.gov/pubmed/36552764
http://dx.doi.org/10.3390/cells11244000