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Development of Monoclonal Antibodies Targeting Canine PD-L1 and PD-1 and Their Clinical Relevance in Canine Apocrine Gland Anal Sac Adenocarcinoma

SIMPLE SUMMARY: In human cancers, the development of PD-1 and PD-L1 inhibitors has dramatically increased survival in many patients, but only recently these molecules have been considered in veterinary medicine. Here, we describe generation of specific canine PD-1 and PD-L1 monoclonal antibodies and...

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Detalles Bibliográficos
Autores principales: Minoli, Lucia, Licenziato, Luca, Kocikowski, Mikolaj, Cino, Marzia, Dziubek, Katarzyna, Iussich, Selina, Fanelli, Antonella, Morello, Emanuela, Martano, Marina, Hupp, Ted, Vojtesek, Borek, Parys, Maciej, Aresu, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9777308/
https://www.ncbi.nlm.nih.gov/pubmed/36551672
http://dx.doi.org/10.3390/cancers14246188