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Development of Monoclonal Antibodies Targeting Canine PD-L1 and PD-1 and Their Clinical Relevance in Canine Apocrine Gland Anal Sac Adenocarcinoma
SIMPLE SUMMARY: In human cancers, the development of PD-1 and PD-L1 inhibitors has dramatically increased survival in many patients, but only recently these molecules have been considered in veterinary medicine. Here, we describe generation of specific canine PD-1 and PD-L1 monoclonal antibodies and...
Autores principales: | Minoli, Lucia, Licenziato, Luca, Kocikowski, Mikolaj, Cino, Marzia, Dziubek, Katarzyna, Iussich, Selina, Fanelli, Antonella, Morello, Emanuela, Martano, Marina, Hupp, Ted, Vojtesek, Borek, Parys, Maciej, Aresu, Luca |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9777308/ https://www.ncbi.nlm.nih.gov/pubmed/36551672 http://dx.doi.org/10.3390/cancers14246188 |
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