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Targeting IRS-1/2 in Uveal Melanoma Inhibits In Vitro Cell Growth, Survival and Migration, and In Vivo Tumor Growth

SIMPLE SUMMARY: Uveal melanoma (UM) is the most common eye cancer in adults and its spreading to the liver has poor outcomes for the patients. There is currently only one therapeutic option for treating UM, hence, there is a need for a better understanding of the biology of UM metastatic spreading i...

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Detalles Bibliográficos
Autores principales: Chattopadhyay, Chandrani, Bhattacharya, Rajat, Roszik, Jason, Khan, Fatima S., Wells, Gabrielle A., Villanueva, Hugo, Qin, Yong, Bhattacharya, Rishav, Patel, Sapna P., Grimm, Elizabeth A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9777326/
https://www.ncbi.nlm.nih.gov/pubmed/36551732
http://dx.doi.org/10.3390/cancers14246247