Cargando…

Targeting IRS-1/2 in Uveal Melanoma Inhibits In Vitro Cell Growth, Survival and Migration, and In Vivo Tumor Growth

SIMPLE SUMMARY: Uveal melanoma (UM) is the most common eye cancer in adults and its spreading to the liver has poor outcomes for the patients. There is currently only one therapeutic option for treating UM, hence, there is a need for a better understanding of the biology of UM metastatic spreading i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chattopadhyay, Chandrani, Bhattacharya, Rajat, Roszik, Jason, Khan, Fatima S., Wells, Gabrielle A., Villanueva, Hugo, Qin, Yong, Bhattacharya, Rishav, Patel, Sapna P., Grimm, Elizabeth A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9777326/ https://www.ncbi.nlm.nih.gov/pubmed/36551732 http://dx.doi.org/10.3390/cancers14246247

Ejemplares similares

Simultaneous Inhibition of the HGF/MET and Erk1/2 Pathways Affect Uveal Melanoma Cell Growth and Migration
por: Chattopadhyay, Chandrani, et al.
Publicado: (2014)

A phase II study of the insulin-like growth factor type I receptor inhibitor IMC-A12 in patients with metastatic uveal melanoma
por: Mattei, Jane, et al.
Publicado: (2020)

Elevated Endogenous SDHA Drives Pathological Metabolism in Highly Metastatic Uveal Melanoma
por: Chattopadhyay, Chandrani, et al.
Publicado: (2019)

Pilot Study of Circulating Tumor Cells in Early-Stage and Metastatic Uveal Melanoma
por: Anand, Kartik, et al.
Publicado: (2019)

Novel treatment paradigms for metastatic uveal melanoma
por: Patel, Sapna P., et al.
Publicado: (2022)

Adjuvant Ipilimumab in High-Risk Uveal Melanoma
por: Fountain, Eric, et al.
Publicado: (2019)

Absence of Intraocular Lymphatic Vessels in Uveal Melanomas with Extrascleral Growth
por: van Beek, Jackelien G. M., et al.
Publicado: (2019)

Immune profiling of uveal melanoma identifies a potential signature associated with response to immunotherapy
por: Qin, Yong, et al.
Publicado: (2020)

Case Report: Neuromyelitis Optica After Treatment of Uveal Melanoma With Nivolumab and Ipilimumab
por: Khimani, Karima, et al.
Publicado: (2022)

Co-Targeting FASN and mTOR Suppresses Uveal Melanoma Growth
por: Han, Anna, et al.
Publicado: (2023)

Uveal Melanoma
por: Papastefanou, Vasilios P., et al.
Publicado: (2011)

Uveal Melanoma
por: Pfeffer, Ulrich
Publicado: (2019)

High Cysteinyl Leukotriene Receptor 1 Expression Correlates with Poor Survival of Uveal Melanoma Patients and Cognate Antagonist Drugs Modulate the Growth, Cancer Secretome, and Metabolism of Uveal Melanoma Cells
por: Slater, Kayleigh, et al.
Publicado: (2020)

Triamcinolone acetonide and anecortave acetate do not stimulate uveal melanoma cell growth
por: el Filali, Mariam, et al.
Publicado: (2008)

Vascular endothelial growth factor expression and inhibition in uveal melanoma cell lines
por: Logan, Patrick, et al.
Publicado: (2013)

Effects of Zeaxanthin on Growth and Invasion of Human Uveal Melanoma in Nude Mouse Model
por: Xu, Xiaoliang L., et al.
Publicado: (2015)

Synergic Interactions Between Hepatic Stellate Cells and Uveal Melanoma in Metastatic Growth
por: Piquet, Léo, et al.
Publicado: (2019)

Intermittent MEK inhibition for the treatment of metastatic uveal melanoma
por: Khan, Shaheer, et al.
Publicado: (2022)

Metastatic Risk Factors Associated with Class 1A Uveal Melanoma Patients
por: Ballhausen, Alexej, et al.
Publicado: (2021)

MRI of Uveal Melanoma
por: Ferreira, Teresa A., et al.
Publicado: (2019)

The biology of uveal melanoma
por: Amaro, Adriana, et al.
Publicado: (2017)

Uveal Melanoma Metastasis
por: Rossi, Ernesto, et al.
Publicado: (2021)

Uveal Melanoma Cells Utilize a Novel Route for Transendothelial Migration
por: Onken, Michael D., et al.
Publicado: (2014)

Interplay between soluble CD74 and macrophage-migration inhibitory factor drives tumor growth and influences patient survival in melanoma
por: Fukuda, Yasunari, et al.
Publicado: (2022)

Stromal fibroblast growth factor 2 reduces the efficacy of bromodomain inhibitors in uveal melanoma
por: Chua, Vivian, et al.
Publicado: (2019)

Correction: Interplay between soluble CD74 and macrophage-migration inhibitory factor drives tumor growth and influences patient survival in melanoma
por: Fukuda, Yasunari, et al.
Publicado: (2022)

A Phase II Study of Glembatumumab Vedotin for Metastatic Uveal Melanoma
por: Hasanov, Merve, et al.
Publicado: (2020)

Gamma knife radiosurgery for the treatment of uveal melanoma and uveal metastases
por: Reynolds, Margaret M., et al.
Publicado: (2017)

Exoresection and Endoresection for Uveal Melanoma
por: Gündüz, Kaan, et al.
Publicado: (2010)

Uveal melanoma: Estimating prognosis
por: Kaliki, Swathi, et al.
Publicado: (2015)

YAP as oncotarget in uveal melanoma
por: Yu, Fa-Xing, et al.
Publicado: (2014)

DNA Methylation and Uveal Melanoma
por: Yang, Zhi-Kun, et al.
Publicado: (2018)

Role of Epigenetics in Uveal Melanoma
por: Li, Yongyun, et al.
Publicado: (2017)

Epidemiology of uveal melanoma in Brazil
por: Lucena, Evandro, et al.
Publicado: (2020)

Spliceosome Mutations in Uveal Melanoma
por: Nguyen, Josephine Q.N., et al.
Publicado: (2020)

Multicentric recurrent uveal melanoma
por: Menon, Vikas, et al.
Publicado: (2020)

Animal Models of Uveal Melanoma
por: Uner, Ogul E., et al.
Publicado: (2022)

Uveal Melanoma Metastasis to the Thyroid
por: Thanadar, Rokshana R., et al.
Publicado: (2023)

Cytospin-A Regulates Colorectal Cancer Cell Division and Migration by Modulating Stability of Microtubules and Actin Filaments
por: Fan, Fan, et al.
Publicado: (2022)

A Comparative Transcriptomic Analysis of Uveal Melanoma and Normal Uveal Melanocyte
por: An, Jianhong, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_t7ro2mv0q140rmiikmi26fmtub