Long-Term Hyperglycemia Causes Depressive Behaviors in Mice with Hypoactive Glutamatergic Activity in the Medial Prefrontal Cortex, Which Is Not Reversed by Insulin Treatment

The etiology of hyperglycemic-induced depressive behaviors is unclear. We hypothesized that long-term hyperglycemia may induce long-lasting disturbances in glutamatergic signaling and neural damages, causing depressive behaviors. To prove our hypothesis, a C57BL/6N mouse model of hyperglycemia was m...

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Detalles Bibliográficos
Autores principales: Baek, Ji Hyeong, Son, Hyeonwi, Kang, Jae Soon, Yoo, Dae Young, Chung, Hye Jin, Lee, Dong Kun, Kim, Hyun Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9777379/
https://www.ncbi.nlm.nih.gov/pubmed/36552776
http://dx.doi.org/10.3390/cells11244012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9777379/
https://www.ncbi.nlm.nih.gov/pubmed/36552776
http://dx.doi.org/10.3390/cells11244012

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