Impact of Liver Inflammation on Bile Acid Side Chain Shortening and Amidation

Bile acid (BA) synthesis from cholesterol by hepatocytes is inhibited by inflammatory cytokines. Whether liver inflammation also affects BA side chain shortening and conjugation was investigated. In human liver cell lines (IHH, HepG2, and HepaRG), agonists of nuclear receptors including the farnesoi...

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Detalles Bibliográficos
Autores principales: Alonso-Peña, Marta, Espinosa-Escudero, Ricardo, Hermanns, Heike M., Briz, Oscar, Herranz, Jose M., Garcia-Ruiz, Carmen, Fernandez-Checa, Jose C., Juamperez, Javier, Avila, Matias, Argemi, Josepmaria, Bataller, Ramon, Crespo, Javier, Monte, Maria J., Geier, Andreas, Herraez, Elisa, Marin, Jose J. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9777420/
https://www.ncbi.nlm.nih.gov/pubmed/36552746
http://dx.doi.org/10.3390/cells11243983

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9777420/
https://www.ncbi.nlm.nih.gov/pubmed/36552746
http://dx.doi.org/10.3390/cells11243983

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