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Impact of Liver Inflammation on Bile Acid Side Chain Shortening and Amidation
Bile acid (BA) synthesis from cholesterol by hepatocytes is inhibited by inflammatory cytokines. Whether liver inflammation also affects BA side chain shortening and conjugation was investigated. In human liver cell lines (IHH, HepG2, and HepaRG), agonists of nuclear receptors including the farnesoi...
Autores principales: | Alonso-Peña, Marta, Espinosa-Escudero, Ricardo, Hermanns, Heike M., Briz, Oscar, Herranz, Jose M., Garcia-Ruiz, Carmen, Fernandez-Checa, Jose C., Juamperez, Javier, Avila, Matias, Argemi, Josepmaria, Bataller, Ramon, Crespo, Javier, Monte, Maria J., Geier, Andreas, Herraez, Elisa, Marin, Jose J. G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9777420/ https://www.ncbi.nlm.nih.gov/pubmed/36552746 http://dx.doi.org/10.3390/cells11243983 |
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