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Dynamic 5-Hydroxymethylcytosine Change: Implication for Aging of Non-Human Primate Brain

Profiling of 5-hydroxymethylcytosine (5hmC) in the brain regions of rhesus monkey at different ages reveals accumulation and tissue-specific patterns of 5hmC with aging. Region-specific differentially hydroxymethylated regions (DhMRs) are involved in neuronal functions and signal transduction. These...

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Detalles Bibliográficos
Autores principales: Liu, Xiaodong, Li, Xiao-Jiang, Lin, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9777599/
https://www.ncbi.nlm.nih.gov/pubmed/36547250
http://dx.doi.org/10.3390/epigenomes6040041