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Integrative Meta-Analysis of Huntington’s Disease Transcriptome Landscape

Huntington’s disease (HD) is a neurodegenerative disorder with autosomal dominant inheritance caused by glutamine expansion in the Huntingtin gene (HTT). Striatal projection neurons (SPNs) in HD are more vulnerable to cell death. The executive striatal population is directly connected with the Brodm...

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Detalles Bibliográficos
Autores principales: Sneha, Nela Pragathi, Dharshini, S. Akila Parvathy, Taguchi, Y.-H., Gromiha, M. Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9777612/
https://www.ncbi.nlm.nih.gov/pubmed/36553652
http://dx.doi.org/10.3390/genes13122385