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A Tet-Inducible CRISPR Platform for High-Fidelity Editing of Human Pluripotent Stem Cells
Pluripotent stem cells (PSCs) offer an exciting resource for probing human biology; however, gene-editing efficiency remains relatively low in many cell types, including stem cells. Gene-editing using the CRISPR-Cas9 system offers an attractive solution that improves upon previous gene-editing appro...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9777998/ https://www.ncbi.nlm.nih.gov/pubmed/36553630 http://dx.doi.org/10.3390/genes13122363 |