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Folic Acid and Vitamin B12 Prevent Deleterious Effects of Rotenone on Object Novelty Recognition Memory and Kynu Expression in an Animal Model of Parkinson’s Disease

Parkinson’s disease (PD) is characterized by a range of motor signs, but cognitive dysfunction is also observed. Supplementation with folic acid and vitamin B12 is expected to prevent cognitive impairment. To test this in PD, we promoted a lesion within the substantia nigra pars compacta of rats usi...

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Detalles Bibliográficos
Autores principales: Kretzschmar, Gabriela Canalli, Targa, Adriano D. S., Soares-Lima, Sheila Coelho, dos Santos, Priscila Ianzen, Rodrigues, Lais S., Macedo, Daniel A., Ribeiro Pinto, Luis Felipe, Lima, Marcelo M. S., Boldt, Angelica Beate Winter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9778036/
https://www.ncbi.nlm.nih.gov/pubmed/36553663
http://dx.doi.org/10.3390/genes13122397