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Folic Acid and Vitamin B12 Prevent Deleterious Effects of Rotenone on Object Novelty Recognition Memory and Kynu Expression in an Animal Model of Parkinson’s Disease
Parkinson’s disease (PD) is characterized by a range of motor signs, but cognitive dysfunction is also observed. Supplementation with folic acid and vitamin B12 is expected to prevent cognitive impairment. To test this in PD, we promoted a lesion within the substantia nigra pars compacta of rats usi...
Autores principales: | Kretzschmar, Gabriela Canalli, Targa, Adriano D. S., Soares-Lima, Sheila Coelho, dos Santos, Priscila Ianzen, Rodrigues, Lais S., Macedo, Daniel A., Ribeiro Pinto, Luis Felipe, Lima, Marcelo M. S., Boldt, Angelica Beate Winter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9778036/ https://www.ncbi.nlm.nih.gov/pubmed/36553663 http://dx.doi.org/10.3390/genes13122397 |
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