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In Vivo Hematopoietic Stem Cell Genome Editing: Perspectives and Limitations

The tremendous evolution of genome-editing tools in the last two decades has provided innovative and effective approaches for gene therapy of congenital and acquired diseases. Zinc-finger nucleases (ZFNs), transcription activator- like effector nucleases (TALENs) and CRISPR-Cas9 have been already ap...

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Detalles Bibliográficos
Autores principales: Psatha, Nikoletta, Paschoudi, Kiriaki, Papadopoulou, Anastasia, Yannaki, Evangelia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9778055/
https://www.ncbi.nlm.nih.gov/pubmed/36553489
http://dx.doi.org/10.3390/genes13122222