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53BP1: Keeping It under Control, Even at a Distance from DNA Damage

Double-strand breaks (DSBs) are toxic lesions that can be generated by exposure to genotoxic agents or during physiological processes, such as during V(D)J recombination. The repair of these DSBs is crucial to prevent genomic instability and to maintain cellular homeostasis. Two main pathways partic...

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Detalles Bibliográficos
Autores principales: Rass, Emilie, Willaume, Simon, Bertrand, Pascale
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9778356/
https://www.ncbi.nlm.nih.gov/pubmed/36553657
http://dx.doi.org/10.3390/genes13122390