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Retinal Photoreceptor Protection in an AMD-Related Mouse Model by Selective Sigma-1 or Sigma-2 Receptor Modulation

The structurally and genetically distinct sigma-1 receptor (S1R) and sigma-2 receptor (S2R) comprise a unique class of drug binding sites. Their alleles are associated with human diseases involving neuronal systems, such as age-related macular degeneration (AMD) characterized by photoreceptor and re...

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Detalles Bibliográficos
Autores principales: Mavlyutov, Timur A., Li, Jing, Liu, Xinying, Shen, Hongtao, Yang, Huan, McCurdy, Christopher R., Pattnaik, Bikash, Guo, Lian-Wang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9778362/
https://www.ncbi.nlm.nih.gov/pubmed/36553653
http://dx.doi.org/10.3390/genes13122386